SCHEMBL28349653

SCHEMBL28349653

O=P1(Oc2ccccc2)Oc2ccccc2Sc2ccccc2O1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.35
RECQL P46063 1/20 0.33
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4102660 0.87 RECQL (0.39) RECQLMAPK1HSD17B10
SCHEMBL15456841 0.74 RECQL (0.38) RECQLMAPK1HSD17B10
SCHEMBL4103106 0.73 TDP1 (0.38)
SCHEMBL29257676 0.70 BCHE (0.38) BCHERECQLMAPK1HSD17B10
SCHEMBL29367391 0.70 BCHE (0.38) BCHERECQLMAPK1HSD17B10
SCHEMBL11698928 0.70 RECQL (0.38) RECQLMAPK1HSD17B10
SCHEMBL5304770 0.69 RECQL (0.35) RECQLMAPK1HSD17B10
SCHEMBL9122026 0.68 MAPT (0.48) ALDH1A1MAPT
SCHEMBL29260495 0.67 RECQL (0.39) RECQLMAPK1HSD17B10
SCHEMBL6663181 0.67 RECQL (0.36) RECQLMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110563760-B Preparation method of phenyl thiodiphenyl phosphate 宜春学院 2022-02-11 CN claimed
CN-110563760-B Preparation method of phenyl thiodiphenyl phosphate 宜春学院 2022-02-11 CN disclosed
CN-110563760-B Preparation method of phenyl thiodiphenyl phosphate 宜春学院 2022-02-11 CN disclosed
CN-110563760-B Preparation method of phenyl thiodiphenyl phosphate 宜春学院 2022-02-11 CN disclosed
CN-110563760-A Preparation method of thiophosphate compound 宜春学院 2019-12-13 CN disclosed