Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.58 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629080 | 0.83 | MRGPRX4 (0.62) | MRGPRX4MAOBHTTPOLBRECQL | |
| SCHEMBL28350008 | 0.81 | POLB (0.64) | MRGPRX4MAOBHTTPOLBRECQL | |
| SCHEMBL28350077 | 0.80 | MRGPRX4 (0.59) | MRGPRX4MAOBHTTSMN1; SMN2ABCB1 | |
| SCHEMBL28349971 | 0.80 | MRGPRX4 (0.59) | MRGPRX4MAOBHTTLMNASMN1; SMN2 | |
| SCHEMBL28347034 | 0.80 | MRGPRX4 (0.59) | MRGPRX4MAOBHTTPOLBRECQL | |
| SCHEMBL28350108 | 0.80 | MRGPRX4 (0.59) | MRGPRX4MAOBHTTPOLBRECQL | |
| SCHEMBL28346699 | 0.80 | MEN1 (0.64) | MRGPRX4MAOBHTTPOLBRECQL | |
| SCHEMBL31318410 | 0.78 | MRGPRX4 (0.74) | MRGPRX4MAOBHTTPOLBRECQL | |
| SCHEMBL5101144 | 0.78 | MRGPRX4 (0.74) | MRGPRX4MAOBHTTPOLBRECQL | |
| SCHEMBL28349589 | 0.76 | MAOB (0.50) | MRGPRX4MAOBHTTPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056630-B | Indane derivative, and synthesis method and medical application thereof | 合肥工业大学 | 2020-01-17 | — | — | CN | disclosed |