Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | Q9HBH1 | 1/20 | 0.41 | |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354223 | 1.00 | HTR2A (0.47) | HTR2APDFSSTR3TGM2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28635685 | 0.95 | HTR2A (0.43) | HTR2APDFSSTR3TGM2ALDH1A1 | |
| SCHEMBL32667911 | 0.92 | HTR2A (0.44) | HTR2APDFSSTR3TGM2ALDH1A1 | |
| SCHEMBL26241697 | 0.91 | HTR2A (0.50) | HTR2APDFSSTR3TGM2ALDH1A1 | |
| SCHEMBL31009020 | 0.90 | HTR2A (0.49) | HTR2APDFSSTR3TGM2ALDH1A1 | |
| SCHEMBL15631789 | 0.90 | HTR2A (0.49) | HTR2APDFSSTR3TGM2ALDH1A1 | |
| SCHEMBL28635684 | 0.89 | HTR2A (0.41) | HTR2APDFSSTR3TGM2ALDH1A1 | |
| SCHEMBL24728317 | 0.89 | HTR2A (0.48) | HTR2APDFSSTR3TGM2ALDH1A1 | |
| SCHEMBL21544417 | 0.89 | HTR2A (0.48) | HTR2APDFSSTR3TGM2ALDH1A1 | |
| SCHEMBL21544416 | 0.89 | HTR2A (0.48) | HTR2APDFSSTR3TGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761635-A | BCL-XL inhibitor antibody drug conjugates and methods of use thereof | 诺华股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-109963870-B | anti-B7-H3 antibodies and antibody drug conjugates | 艾伯维公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116284404-A | anti-B7-H3 antibodies and antibody drug conjugates | 艾伯维公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116173232-A | anti-CD 98 antibodies and antibody drug conjugates | 艾伯维公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-116059201-A | anti-EGFR antibody drug conjugates | 艾伯维公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-116059202-A | anti-EGFR antibody drug conjugates | 艾伯维公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-116059394-A | anti-EGFR antibody drug conjugates | 艾伯维公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-109562170-B | anti-CD 98 antibodies and antibody drug conjugates | 艾伯维公司（US） | 2023-01-13 | — | — | CN | disclosed |
| CN-111620861-A | BCL-XL inhibitory compound having low cell permeability and antibody drug conjugate including the same | 艾伯维公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-107660208-B | Bifunctional cytotoxic agents comprising a CTI pharmacophore | 辉瑞公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-111051329-A | Hamiltrin derivatives and antibody drug complexes thereof | 大日本住友制药株式会社 | 2020-04-21 | — | — | CN | disclosed |
| CN-110678183-A | Antibody conjugates comprising TOLL-like receptor agonists and combination therapies | 诺华股份有限公司 | 2020-01-10 | — | — | CN | disclosed |