Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ESRRB | O95718 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271528 | 0.84 | ESR1 (1.00) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 | |
| SCHEMBL6064527 | 0.84 | ESR1 (1.00) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 | |
| SCHEMBL13270171 | 0.84 | ESR1 (1.00) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 | |
| SCHEMBL1271527 | 0.84 | ESR1 (1.00) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 | |
| SCHEMBL1332731 | 0.84 | ESR1 (1.00) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 | |
| SCHEMBL2833765 | 0.81 | ESR1 (0.74) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 | |
| SCHEMBL6898066 | 0.81 | ESR1 (0.71) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 | |
| SCHEMBL6064623 | 0.80 | ESR1 (0.73) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 | |
| SCHEMBL6064626 | 0.80 | ESR1 (0.73) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 | |
| SCHEMBL2835911 | 0.80 | ESR1 (0.73) | ESR1LMNASMN1; SMN2MAPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242619-B1 | BEHAVIORAL OR PHYSIOLOGICAL RESPONSE, REDUCTION OF NEGATIVE AFFECT, MOOD, AND CHARACTER TRAITS; NASAL ADMINISTRATION OF VOMEROPHERINS OR PHEROMONES, NERVOUS SYSTEM DRUG MODE | PHERIN PHARMACEUTICALS, INC. | 2001-06-05 | — | — | US | claimed |
| US-20100111896-A1 | Items Containing A Human Pheromone Component | MARENBERG BARRY J | 2010-05-06 | — | — | US | disclosed |