Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301049 | 1.00 | ATM (0.41) | ATMCTSKPPARACTSSAPP | |
| SCHEMBL19300691 | 0.92 | ATM (0.42) | ATMCTSKPPARACTSSAPP | |
| SCHEMBL28411906 | 0.92 | ATM (0.42) | ATMCTSKPPARACTSSAPP | |
| SCHEMBL19285490 | 0.89 | CYP3A4 (0.32) | CTSK | |
| SCHEMBL20494817 | 0.89 | CYP3A4 (0.32) | CTSK | |
| SCHEMBL23166477 | 0.88 | CA1 (0.42) | ATMCTSKPPARACTSSAPP | |
| SCHEMBL19300900 | 0.88 | CA1 (0.42) | ATMCTSKPPARACTSSAPP | |
| SCHEMBL28408779 | 0.88 | ATM (0.43) | ATMCTSKPPARACTSSAPP | |
| SCHEMBL19300689 | 0.88 | ATM (0.43) | ATMCTSKPPARACTSSAPP | |
| SCHEMBL5220048 | 0.86 | ATM (0.45) | ATMCTSKPPARACTSSPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770224-B | Indole derivatives as efflux pump inhibitors | 罗格斯新泽西州立大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-110770224-A | Indole derivatives as efflux pump inhibitors | 罗格斯新泽西州立大学 | 2020-02-07 | — | — | CN | disclosed |