⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131152 | 0.95 | IRAK4 (0.30) | — | |
| SCHEMBL16866823 | 0.90 | — | — | |
| SCHEMBL14617222 | 0.81 | — | — | |
| SCHEMBL14617217 | 0.81 | — | — | |
| SCHEMBL17069181 | 0.79 | IRAK4 (0.34) | — | |
| SCHEMBL28656478 | 0.76 | — | — | |
| SCHEMBL14486972 | 0.75 | — | — | |
| SCHEMBL12605742 | 0.73 | — | — | |
| SCHEMBL12448231 | 0.73 | EPHX1 (0.42) | — | |
| SCHEMBL2741638 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9831448-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-8399520-B2 | Selective estrogen receptor modulator | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20120004315-A1 | Selective Estrogen Receptor Modulator | RADIUS HEALTH, INC. | 2012-01-05 | — | — | US | disclosed |
| US-7612114-B2 | Such as (R)-6-{2-{ethyl[4-(2-ethylaminoethyl)benzyl]amino }-4-methoxyphenyl }-5,6,7,8-tetrahydronaphthalen-2-ol; osteoporosis; breast cancer | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |