Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19045869 | 0.78 | IRAK4 (0.55) | IRAK4 | |
| SCHEMBL19030273 | 0.74 | IRAK4 (0.48) | IRAK4 | |
| SCHEMBL19030256 | 0.74 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL24375562 | 0.72 | IRAK4 (0.60) | IRAK4 | |
| SCHEMBL20594823 | 0.70 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL19030431 | 0.69 | IRAK4 (0.50) | IRAK4 | |
| SCHEMBL28654060 | 0.68 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL21840503 | 0.68 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21840497 | 0.67 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21840557 | 0.67 | IRAK4 (1.00) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770229-A | Benzofuran compounds as IRAK4 modulators | 豪夫迈·罗氏有限公司 | 2020-02-07 | — | — | CN | disclosed |