SCHEMBL28358262

SCHEMBL28358262

CCC(C)OC(=O)OCCCl

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
ALDH1A1 P00352 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28358446 1.00 MAPT (0.34) MAPTALDH1A1FAAH
SCHEMBL28358260 1.00 MAPT (0.34) MAPTALDH1A1FAAH
SCHEMBL31731277 0.87 MAPT (0.38) MAPTALDH1A1FAAH
SCHEMBL11144445 0.86 MAPK1 (0.37)
SCHEMBL12986333 0.83 MAPT (0.36) MAPTALDH1A1FAAH
SCHEMBL12986377 0.83 MAPT (0.36) MAPTALDH1A1FAAH
SCHEMBL12986335 0.83 MAPT (0.36) MAPTALDH1A1FAAH
SCHEMBL2984925 0.83 HCAR2 (0.36) MAPTALDH1A1FAAH
SCHEMBL4439901 0.83 HCAR2 (0.36) MAPTALDH1A1FAAH
SCHEMBL2982786 0.83 HCAR2 (0.36) MAPTALDH1A1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110655490-A Halogenated imidazole compounds, preparation method and application 重庆迈迪生医药科技有限公司 2020-01-07 CN disclosed