Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 19/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 16/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28361875 | 0.82 | HCRTR2 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL28358266 | 0.81 | HCRTR2 (0.55) | HCRTR2HCRTR1 | |
| SCHEMBL29912327 | 0.81 | HCRTR2 (0.55) | HCRTR2HCRTR1 | |
| SCHEMBL28361860 | 0.79 | HCRTR2 (0.50) | HCRTR2HCRTR1 | |
| SCHEMBL29912155 | 0.79 | HCRTR1 (0.56) | HCRTR2HCRTR1 | |
| SCHEMBL28883566 | 0.79 | HCRTR1 (0.56) | HCRTR2HCRTR1 | |
| SCHEMBL17510503 | 0.77 | HCRTR2 (0.60) | HCRTR2HCRTR1 | |
| SCHEMBL17510504 | 0.77 | HCRTR2 (0.60) | HCRTR2HCRTR1 | |
| SCHEMBL28361848 | 0.73 | HCRTR1 (0.54) | HCRTR2HCRTR1 | |
| SCHEMBL16148897 | 0.71 | HCRTR2 (1.00) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669052-A | Substituted 2-azabicyclic compounds and their use as orexin receptor modulators | 詹森药业有限公司 | 2020-01-10 | — | — | CN | disclosed |