Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24283657 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL28358659 | 0.98 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL28358658 | 0.98 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL24283687 | 0.86 | MAPK1 (0.46) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL21298740 | 0.86 | MAPK1 (0.46) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL24283695 | 0.85 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL24283641 | 0.85 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL21298730 | 0.85 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL24283748 | 0.85 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL28358415 | 0.85 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110655490-A | Halogenated imidazole compounds, preparation method and application | 重庆迈迪生医药科技有限公司 | 2020-01-07 | — | — | CN | disclosed |