Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL28333110 | 0.97 | TP53 (0.73) | TP53FFAR3LCKFYNTSHR | |
| Lactic Acid SCHEMBL8948591 | 0.96 | TP53 (0.85) | TP53FFAR3LCKFYNTSHR | |
| Lactic Acid SCHEMBL27710699 | 0.96 | TP53 (0.85) | TP53FFAR3LCKFYNTSHR | |
| Lactic Acid SCHEMBL6264768 | 0.96 | TP53 (0.85) | TP53FFAR3LCKFYNTSHR | |
| Lactic Acid SCHEMBL6943476 | 0.96 | TP53 (0.85) | TP53FFAR3LCKFYNTSHR | |
| Lactic Acid SCHEMBL1018571 | 0.96 | TP53 (0.85) | TP53FFAR3LCKFYNTSHR | |
| Lactic Acid SCHEMBL25357648 | 0.93 | TP53 (0.79) | TP53FFAR3LCKFYNTSHR | |
| Lactic Acid SCHEMBL9418456 | 0.93 | TP53 (0.79) | TP53FFAR3LCKFYNTSHR | |
| Lactic Acid SCHEMBL1741441 | 0.93 | TP53 (0.79) | TP53FFAR3LCKFYNTSHR | |
| Lactic Acid SCHEMBL915747 | 0.93 | TP53 (0.79) | TP53FFAR3LCKFYNTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831914-A | Methods and compositions for improving nutrient acquisition in plants | 欧洲化学农业有限公司 | 2020-02-21 | — | — | CN | disclosed |