SCHEMBL28362105

SCHEMBL28362105

NCCCCCCNC(=O)c1ccc(F)cc1

nearest known ligand 0.80

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 5/20 0.60
HDAC3 O15379 4/20 0.60
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
HDAC6 Q9UBN7 6/20 0.57
NAMPT P43490 2/20 0.57
MAPK1 P28482 1/20 0.56
NCOR2 Q9Y618 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27996132 1.00 HDAC1 (0.60) HDAC1HDAC3NPC1RAB9AHDAC6
SCHEMBL6378992 0.93 NPC1 (0.62) HDAC1HDAC3NPC1RAB9AHDAC6
SCHEMBL26709560 0.91 MAPK1 (0.65) HDAC1HDAC3NPC1RAB9AHDAC6
SCHEMBL12960847 0.91 MAPK1 (0.65) HDAC1HDAC3NPC1RAB9AHDAC6
SCHEMBL3523157 0.89 MAPK1 (0.61) HDAC1HDAC3NPC1RAB9AHDAC6
SCHEMBL3505666 0.86 CYP1A2 (0.68) HDAC1HDAC3NPC1RAB9A
SCHEMBL21000000 0.85 NAMPT (0.57) HDAC1HDAC3NPC1RAB9AHDAC6
SCHEMBL29582367 0.85 NPC1 (0.65) HDAC1HDAC3NPC1RAB9AHDAC6
SCHEMBL28038483 0.85 MAPK1 (0.57) HDAC1HDAC3NPC1RAB9AHDAC6
SCHEMBL13566561 0.85 MAPK1 (0.62) HDAC1HDAC3NPC1RAB9AHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107459816-B High-temperature-resistant enhanced thermoplastic composite material and preparation method thereof 四川大学 2020-01-17 CN disclosed