Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104548 | 0.91 | KCNH2 (0.50) | KCNH2SCN3AKMT2AMEN1HPGD | |
| SCHEMBL2831532 | 0.85 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL2712980 | 0.82 | MAOB (0.49) | KCNH2SCN3ASMN1; SMN2PARP15PARP10 | |
| SCHEMBL22534101 | 0.82 | MAOB (0.49) | KCNH2SCN3ASMN1; SMN2PARP15PARP10 | |
| SCHEMBL13311482 | 0.81 | SCN3A (0.43) | KCNH2SCN3AKMT2AMEN1HPGD | |
| SCHEMBL12973320 | 0.79 | KCNH2 (0.51) | KCNH2SCN3AALDH1A1 | |
| SCHEMBL2832345 | 0.76 | MAOB (0.50) | KCNH2SCN3APARP15PARP10 | |
| SCHEMBL22546709 | 0.76 | MAOB (0.49) | KCNH2SCN3AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL310302 | 0.76 | MAOB (0.49) | KCNH2SCN3AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29385120 | 0.76 | MAOB (0.49) | KCNH2SCN3AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803833-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2010-09-28 | — | — | US | disclosed |