Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.59 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.31 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18770572 | 1.00 | AAK1 (0.59) | AAK1CYSLTR2CYSLTR1CES1HDAC3 | |
| SCHEMBL28367717 | 1.00 | AAK1 (0.59) | AAK1CYSLTR2CYSLTR1CES1HDAC3 | |
| SCHEMBL16371038 | 0.91 | AAK1 (0.68) | AAK1CES1HDAC3TSHRALDH1A1 | |
| SCHEMBL28269214 | 0.84 | AAK1 (0.65) | AAK1CES1TSHRALDH1A1MMP8 | |
| SCHEMBL28367638 | 0.84 | AAK1 (0.46) | AAK1CES1TSHRALDH1A1PPARG | |
| SCHEMBL28367899 | 0.84 | AAK1 (0.46) | AAK1CES1TSHRALDH1A1PPARG | |
| SCHEMBL18762620 | 0.84 | AAK1 (0.46) | AAK1CES1TSHRALDH1A1PPARG | |
| SCHEMBL18762429 | 0.83 | AAK1 (0.86) | AAK1CYSLTR2CYSLTR1TSHRALDH1A1 | |
| SCHEMBL18762427 | 0.83 | AAK1 (0.86) | AAK1CYSLTR2CYSLTR1TSHRALDH1A1 | |
| SCHEMBL18762563 | 0.83 | AAK1 (0.86) | AAK1CYSLTR2CYSLTR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809467-A | Modulators of SESTRIN-GATOR2 interaction and uses thereof | 纳维托制药有限公司 | 2020-02-18 | — | — | CN | disclosed |