Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21847019 | 0.94 | EGFR (0.60) | EGFRALKMET | |
| SCHEMBL29832835 | 0.94 | EGFR (0.60) | EGFRALKMET | |
| SCHEMBL28368546 | 0.92 | EGFR (0.69) | EGFRALKMET | |
| SCHEMBL28364828 | 0.88 | EGFR (0.64) | EGFRALKMET | |
| SCHEMBL21847024 | 0.87 | EGFR (0.56) | EGFRALK | |
| SCHEMBL21847026 | 0.86 | EGFR (0.70) | EGFRALKMET | |
| SCHEMBL21846985 | 0.84 | ALK (0.54) | EGFRALK | |
| SCHEMBL21847032 | 0.82 | EGFR (0.65) | EGFRALKMET | |
| SCHEMBL28364747 | 0.81 | EGFR (0.75) | EGFRALK | |
| SCHEMBL18181767 | 0.81 | ALK (0.60) | EGFRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110740999-A | N2, N4-diphenylpyrimidine-2, 4-diamine derivative, process for producing the same, and pharmaceutical composition for preventing or treating cancer comprising the same as active ingredient | 韩国化学研究院 | 2020-01-31 | — | — | CN | disclosed |