Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16808624 | 1.00 | TSHR (0.44) | TSHRHDAC4POLBGAACYP2D6 | |
| SCHEMBL18186731 | 1.00 | TSHR (0.44) | TSHRHDAC4POLBGAACYP2D6 | |
| SCHEMBL16808494 | 1.00 | TSHR (0.44) | TSHRHDAC4POLBGAACYP2D6 | |
| SCHEMBL28365208 | 1.00 | TSHR (0.44) | TSHRHDAC4POLBGAACYP2D6 | |
| SCHEMBL16808388 | 0.85 | TSHR (0.40) | TSHRPOLBGAACYP2D6SLC6A4 | |
| SCHEMBL16808475 | 0.85 | HDAC4 (0.41) | TSHRHDAC4POLBGAACYP2D6 | |
| SCHEMBL16808609 | 0.85 | TSHR (0.40) | TSHRPOLBCYP2D6SLC6A4SLC6A3 | |
| SCHEMBL16808461 | 0.85 | HDAC4 (0.41) | TSHRHDAC4POLBGAACYP2D6 | |
| SCHEMBL18801893 | 0.85 | TSHR (0.40) | TSHRPOLBGAACYP2D6SLC6A4 | |
| SCHEMBL27085624 | 0.85 | HDAC4 (0.41) | TSHRHDAC4POLBGAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106507667-B | Sulfamate derivatives for the prevention or treatment of epilepsy | 比皮艾思药物研发有限公司 | 2020-01-24 | — | — | CN | disclosed |