Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.62 |
| ▸ | RPS6KA2 | Q15349 | 15/20 | 0.58 |
| ▸ | RPS6KA3 | P51812 | 7/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101785 | 0.92 | MAPKAPK2 (0.75) | MAPKAPK2RPS6KA2RPS6KA3 | |
| SCHEMBL17361103 | 0.88 | MAPKAPK2 (0.55) | MAPKAPK2RPS6KA2RPS6KA3 | |
| SCHEMBL17368554 | 0.87 | RPS6KA2 (0.55) | MAPKAPK2RPS6KA2RPS6KA3 | |
| SCHEMBL17361108 | 0.86 | MAPKAPK2 (0.57) | MAPKAPK2RPS6KA2RPS6KA3 | |
| SCHEMBL16123467 | 0.86 | MAPKAPK2 (0.57) | MAPKAPK2RPS6KA2RPS6KA3 | |
| SCHEMBL3084607 | 0.79 | RPS6KA2 (0.88) | MAPKAPK2RPS6KA2RPS6KA3 | |
| SCHEMBL16101276 | 0.77 | MAPKAPK2 (1.00) | MAPKAPK2RPS6KA2RPS6KA3 | |
| SCHEMBL16123119 | 0.75 | MAPKAPK2 (0.77) | MAPKAPK2RPS6KA2RPS6KA3 | |
| SCHEMBL16101147 | 0.74 | MAPKAPK2 (0.52) | MAPKAPK2RPS6KA2RPS6KA3 | |
| SCHEMBL12598199 | 0.74 | RPS6KA2 (1.00) | MAPKAPK2RPS6KA2RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746424-A | MK2 inhibitors and uses thereof | 西建卡尔有限责任公司 | 2020-02-04 | — | — | CN | disclosed |