Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201986 | 0.98 | TLR8 (0.39) | TLR8NPC1RAB9ALMNAHTT | |
| SCHEMBL9661568 | 0.98 | TLR8 (0.39) | TLR8NPC1RAB9ALMNAHTT | |
| SCHEMBL27971467 | 0.98 | TLR8 (0.39) | TLR8NPC1RAB9ALMNAHTT | |
| SCHEMBL7515138 | 0.98 | TLR8 (0.39) | TLR8NPC1RAB9ALMNAHTT | |
| SCHEMBL27967373 | 0.98 | TLR8 (0.39) | TLR8NPC1RAB9ALMNAHTT | |
| Hydrochloric Acid SCHEMBL29011515 | 0.96 | TLR8 (0.38) | TLR8NPC1RAB9ALMNAHTT | |
| Hydrochloric Acid SCHEMBL28575648 | 0.96 | TLR8 (0.38) | TLR8NPC1RAB9ALMNAHTT | |
| Hydrochloric Acid SCHEMBL29027485 | 0.94 | TLR8 (0.37) | TLR8CYP1A2CYP3A4TSHR | |
| Bromide SCHEMBL29165610 | 0.92 | TSHR (0.39) | TLR8SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL29089622 | 0.91 | TLR8 (0.36) | TLR8TSHRPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113789581-A | Preparation method of novel antibacterial fiber | 东部湾(扬州)生物新材料有限公司 | 2021-12-14 | — | — | CN | claimed |
| CN-113789582-A | Preparation method of antibacterial polypropylene fiber | 东部湾(扬州)生物新材料有限公司 | 2021-12-14 | — | — | CN | claimed |
| CN-113318762-A | Preparation method and application of flower-ball-shaped bismuth oxybromide-coated zinc oxide nanorod visible-light-driven photocatalyst | 桂林理工大学 | 2021-08-31 | — | — | CN | claimed |
| CN-110860300-B | 3DWO 3 /BiOBr photocatalyst and preparation method and application thereof | 湘潭大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-114891247-A | Preparation method of composite flame-retardant plastic | 江苏中科睿赛污染控制工程有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-113789581-A | Preparation method of novel antibacterial fiber | 东部湾(扬州)生物新材料有限公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-113789582-A | Preparation method of antibacterial polypropylene fiber | 东部湾(扬州)生物新材料有限公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-113789581-A | Preparation method of novel antibacterial fiber | 东部湾(扬州)生物新材料有限公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-113318762-A | Preparation method and application of flower-ball-shaped bismuth oxybromide-coated zinc oxide nanorod visible-light-driven photocatalyst | 桂林理工大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-110860300-A | 3DWO3/BiOBr photocatalyst and preparation method and application thereof | 湘潭大学 | 2020-03-06 | — | — | CN | disclosed |