Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 19/20 | 0.84 |
| ▸ | IDH2 | P48735 | 5/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21573279 | 0.95 | IDH1 (0.84) | IDH1IDH2 | |
| SCHEMBL16393286 | 0.92 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL16392765 | 0.87 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL29975769 | 0.87 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL28363063 | 0.87 | IDH1 (0.85) | IDH1IDH2 | |
| SCHEMBL28363168 | 0.83 | IDH1 (0.85) | IDH1IDH2 | |
| SCHEMBL22271216 | 0.81 | IDH1 (0.82) | IDH1IDH2 | |
| SCHEMBL16392860 | 0.81 | IDH1 (0.61) | IDH1IDH2 | |
| SCHEMBL22271237 | 0.80 | IDH1 (0.79) | IDH1IDH2 | |
| SCHEMBL21573323 | 0.79 | NPSR1 (0.59) | IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111087353-B | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |
| CN-111087353-A | Therapeutically active compounds and methods of use thereof | 安吉奥斯医药品有限公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-105473560-B | Therapeutically active compounds and methods of use thereof | 安吉奥斯医药品有限公司 | 2020-01-17 | — | — | CN | disclosed |