SCHEMBL28367402

SCHEMBL28367402

CC(C)(C)OC(=O)NC(CO)C(O)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA7 P43166 1/20 0.51
CTSK P43235 10/20 0.43
CYP2D6 P10635 1/20 0.43
GAA P10253 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CTSS P25774 7/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
KLK5 Q9Y337 2/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28367401 1.00 CA1 (0.51) CA1CA2CA7CTSKCYP2D6
SCHEMBL4182916 0.86 CA1 (0.51) CA1CA2CA7CTSKCYP2D6
SCHEMBL5460214 0.86 CA1 (0.51) CA1CA2CA7CTSKCYP2D6
SCHEMBL3880331 0.86 CA1 (0.51) CA1CA2CA7CTSKCYP2D6
SCHEMBL3614140 0.86 CA1 (0.51) CA1CA2CA7CTSKCYP2D6
SCHEMBL19076115 0.85 CA1 (0.50) CA1CA2CA7CTSKCYP2D6
SCHEMBL2641383 0.85 CA1 (0.50) CA1CA2CA7CTSKCYP2D6
SCHEMBL4177443 0.85 CA1 (0.50) CA1CA2CA7CTSKCYP2D6
SCHEMBL2641382 0.85 CA1 (0.50) CA1CA2CA7CTSKCYP2D6
SCHEMBL20024478 0.84 CA1 (0.56) CA1CA2CA7CTSKCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106905386-B Aminoglycoside derivatives 莱姆派克斯制药公司 2020-03-27 CN disclosed