Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.33 |
| ▸ | VEGFA | P15692 | 3/20 | 0.33 |
| ▸ | ARNT | P27540 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505116 | 1.00 | KCNH2 (0.40) | KCNH2MEN1LMNAMAPTRAB9A | |
| SCHEMBL12127371 | 0.81 | KCNH2 (0.43) | KCNH2EPAS1VEGFAARNTCYP3A4 | |
| SCHEMBL16953550 | 0.81 | KCNH2 (0.34) | KCNH2MEN1LMNAMAPTRAB9A | |
| SCHEMBL29639661 | 0.79 | EPAS1 (0.45) | EPAS1VEGFA | |
| SCHEMBL22081868 | 0.78 | ADORA1 (0.34) | MAPTEPAS1 | |
| SCHEMBL12134589 | 0.78 | KCNH2 (0.40) | KCNH2LMNAEPAS1VEGFA | |
| SCHEMBL16956085 | 0.78 | EPAS1 (0.30) | EPAS1 | |
| SCHEMBL16962117 | 0.78 | EPAS1 (0.30) | EPAS1 | |
| SCHEMBL16955986 | 0.75 | MAPT (0.35) | KCNH2LMNAMAPTNPSR1EPAS1 | |
| SCHEMBL508238 | 0.75 | KCNH2 (0.39) | KCNH2MAPTEPAS1VEGFAARNT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110885291-B | Synthetic method of 3-chloro-5- (difluoromethoxy) benzylamine | 阿里生物新材料（常州）有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-110885291-A | Synthetic method of 3-chloro-5- (difluoromethoxy) benzylamine | 阿里生物新材料（常州）有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-110885291-B | Synthetic method of 3-chloro-5- (difluoromethoxy) benzylamine | 阿里生物新材料（常州）有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-110885291-A | Synthetic method of 3-chloro-5- (difluoromethoxy) benzylamine | 阿里生物新材料（常州）有限公司 | 2020-03-17 | — | — | CN | disclosed |