Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 7/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219754 | 1.00 | CTSA (0.42) | CTSASCN9ACASRPTGDR2TP53 | |
| SCHEMBL30541459 | 1.00 | CTSA (0.42) | CTSASCN9ACASRPTGDR2TP53 | |
| SCHEMBL28373915 | 0.88 | SCN9A (0.39) | CTSASCN9ARXRAAPPPDE2A | |
| SCHEMBL30541286 | 0.88 | SCN9A (0.39) | CTSASCN9ARXRAAPPPDE2A | |
| SCHEMBL30541371 | 0.88 | AKR1C3 (0.42) | CTSASCN9AMAPTHPGDNPSR1 | |
| SCHEMBL28373473 | 0.88 | AKR1C3 (0.42) | CTSASCN9AMAPTHPGDNPSR1 | |
| SCHEMBL20545409 | 0.87 | PTGDR2 (0.43) | CTSASCN9APTGDR2TP53MAPT | |
| SCHEMBL30541542 | 0.86 | CTSA (0.43) | CTSAPTGDR2SMN1; SMN2 | |
| SCHEMBL28372548 | 0.86 | CTSA (0.43) | CTSAPTGDR2SMN1; SMN2 | |
| SCHEMBL20545832 | 0.86 | CTSA (0.47) | CTSACASRPTGDR2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914242-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-110914242-A | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2020-03-24 | — | — | CN | disclosed |