SCHEMBL2836945

SCHEMBL2836945

O=C1C=CC(=O)C(=S(=O)=O)C1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.48
GSK3B P49841 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2585204 0.69
SCHEMBL277815 0.67
Formaldehyde SCHEMBL28980261 0.67 GSK3A (0.50) GSK3AGSK3B
Hydrochloric Acid SCHEMBL27827986 0.65 GSK3A (0.56) GSK3AGSK3B
SCHEMBL127160 0.63
SCHEMBL188365 0.63
SCHEMBL366153 0.62 GSK3A (0.71) GSK3AGSK3B
Methane SCHEMBL23038597 0.62 GSK3A (0.50) GSK3AGSK3B
SCHEMBL27851335 0.60 GSK3A (0.48) GSK3AGSK3B
Naphthalene SCHEMBL29090118 0.59 GSK3A (0.40) GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460996-B1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative OREAL (FR) 1994-09-14 EP claimed
EP-0460996-A1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative L'OREAL (FR) 1991-12-11 EP claimed
EP-0376776-A2 Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone L'OREAL (FR) 1990-07-04 EP claimed
US-7718722-B2 Alkylthio- and aryl(heteroyl)thio-substituted p-phenylenediamines, their manufacture and their use in rubber FLEXSYS AMERICA L.P. (US) 2010-05-18 US disclosed
EP-1335900-B1 ALKYLTHIO- AND ARYL(HETEROYL)THIO-SUBSTITUTED P-PHENYLENEDIAMINES, THEIR MANUFACTURE AND THEIR USE IN RUBBER FLEXSYS AMERICA LP (US) 2007-04-18 EP disclosed
US-20040006162-A1 Alkylthio- and aryl(heteroyl)thio-substituted p-phenylenediamines, their manufacture and their use in rubber SOLUTIA INC. 2004-01-08 US disclosed
EP-1335900-A2 ALKYLTHIO- AND ARYL(HETEROYL)THIO-SUBSTITUTED P-PHENYLENEDIAMINES, THEIR MANUFACTURE AND THEIR USE IN RUBBER Flexsys America L.P. (US) 2003-08-20 EP disclosed
US-20020132888-A1 Alkylthio-and aryl(heteroyl)thio-substituted p-phenylenediamines, their manufacture and their use in rubber FLEXSYS AMERICA L.P. 2002-09-19 US disclosed
WO-2002042262-A2 ALKYLTHIO- AND ARYL(HETEROYL)THIO-SUBSTITUTED P-PHENYLENEDIAMINES, THEIR MANUFACTURE AND THEIR USE IN RUBBER FLEXSYS AMERICA L.P. (US) 2002-05-30 WO disclosed
EP-0826668-B1 Derivatives of 2-imino-2,3-dihydro-1H-indole and their use in hair dyeing compositions OREAL (FR) 1999-06-30 EP disclosed
EP-0826668-A1 Derivatives of 2-imino-2,3-dihydro-1H-indole and their use in hair dyeing compositions L'OREAL (FR) 1998-03-04 EP disclosed
EP-0603322-B1 DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES OREAL (FR) 1996-12-11 EP disclosed
EP-0460996-B1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative OREAL (FR) 1994-09-14 EP disclosed
EP-0603322-A1 DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES. OREAL (FR) 1994-06-29 EP disclosed
WO-1993005018-A1 DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES L'OREAL (FR) 1993-03-18 WO disclosed
EP-0376776-B1 PROCESS FOR DYEING KERATINOUS FIBRES WITH HYDROXYINDOLE ASSOCIATED WITH QUINONE AND 1,4-BENZOQUINONE L'OREAL (FR) 1992-09-23 EP disclosed
EP-0460996-A1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative L'OREAL (FR) 1991-12-11 EP disclosed
EP-0376776-A2 Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone L'OREAL (FR) 1990-07-04 EP disclosed