Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 7/20 | 0.66 |
| ▸ | CDC25A | P30304 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28366322 | 0.88 | PLK1 (0.67) | PLK1CDC25AALDH1A1LMNAMCL1 | |
| SCHEMBL28365640 | 0.87 | PLK1 (0.67) | PLK1CDC25AALDH1A1LMNAMCL1 | |
| SCHEMBL3743075 | 0.83 | CDC25A (0.70) | PLK1CDC25AALDH1A1LMNAMCL1 | |
| SCHEMBL18180209 | 0.81 | CDC25A (0.63) | PLK1CDC25AALDH1A1LMNAMCL1 | |
| SCHEMBL15747715 | 0.80 | CDC25A (0.80) | PLK1CDC25AALDH1A1LMNAMCL1 | |
| SCHEMBL28369902 | 0.80 | CDC25A (0.66) | PLK1CDC25AALDH1A1LMNAMCL1 | |
| SCHEMBL28365715 | 0.78 | CDC25A (0.53) | PLK1CDC25AALDH1A1LMNAMCL1 | |
| SCHEMBL15747729 | 0.78 | CDC25A (0.90) | PLK1CDC25AALDH1A1LMNAMCL1 | |
| SCHEMBL2187777 | 0.77 | CDC25A (0.59) | PLK1CDC25AALDH1A1LMNAMCL1 | |
| SCHEMBL2429439 | 0.77 | CDC25A (0.97) | PLK1CDC25AALDH1A1MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107174581-B | Application of N-alkyl indole compounds in preparation of anti-HIV (human immunodeficiency Virus) medicines | 中国医学科学院药物研究所 | 2020-05-01 | — | — | CN | disclosed |
| CN-107151223-B | Application of N-alkyl indole compounds in preparation of anti-influenza virus drugs | 中国医学科学院药物研究所 | 2020-03-31 | — | — | CN | disclosed |
| CN-107151231-B | Indole compounds with antiviral activity | 中国医学科学院药物研究所 | 2020-03-27 | — | — | CN | disclosed |