SCHEMBL2837013

SCHEMBL2837013

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nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
ALDH1A1 P00352 3/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP2C19 P33261 1/20 0.42
LMNA P02545 2/20 0.35
TGM2 P21980 4/20 0.34
FGFR4 P22455 1/20 0.33
F13A1 P00488 1/20 0.32
TGM1 P22735 1/20 0.32
TGM3 Q08188 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
ACACB O00763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20613908 1.00 TSHR (0.59) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL151457 1.00 TSHR (0.59) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL18755249 1.00 TSHR (0.59) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL23420244 0.88 TSHR (0.54) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL29026250 0.87 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL19142357 0.86 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL3932401 0.86 TSHR (0.70) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL3888297 0.85 TSHR (0.62) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL28341390 0.85 TSHR (0.62) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL24152892 0.84 TSHR (0.45) TSHRALDH1A1MAPK1TDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7858561-B2 Degradable polymers for wellbore fluids and processes SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2010-12-28 US disclosed
US-20090075845-A1 Degradable Polymers for Wellbore Fluids and Processes SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2009-03-19 US disclosed
CN-101133231-A Degradable polymers for wellbore fluids and processes SCHLUMBERGER TECHNOLOGY BV (NL) 2008-02-27 CN disclosed
WO-2006075154-A1 DEGRADABLE POLYMERS FOR WELLBORE FLUIDS AND PROCESSES SCHLUMBERGER TECHNOLOGY B. V. (NL) 2006-07-20 WO disclosed
EP-1219416-B1 On-press development printing method using a negative working thermally sensitive lithographic printing plate AGFA GEVAERT (BE) 2004-08-04 EP disclosed
EP-1219416-A1 On-press development printing method using a negative working thermally sensitive lithographic printing plate Agfa-Gevaert (BE) 2002-07-03 EP disclosed