Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21903891 | 0.85 | BTK (0.44) | BTKEGFR | |
| SCHEMBL21965241 | 0.84 | BTK (0.36) | KDRFGFR3MAPTBTKCYP1A2 | |
| SCHEMBL22009288 | 0.80 | BTK (0.35) | KDRFGFR3BTK | |
| SCHEMBL21903856 | 0.79 | BTK (0.41) | KDRFGFR3BTKCYP1A2CYP3A4 | |
| SCHEMBL21903852 | 0.79 | BTK (0.41) | KDRFGFR3BTKCYP1A2CYP3A4 | |
| SCHEMBL31684267 | 0.78 | BTK (0.45) | BTKEGFR | |
| SCHEMBL21903750 | 0.78 | BTK (0.45) | BTKEGFR | |
| SCHEMBL21965629 | 0.78 | IRAK1 (0.42) | KDRFGFR3MAPTBTK | |
| SCHEMBL21903725 | 0.75 | BTK (0.51) | BTKEGFR | |
| SCHEMBL21903730 | 0.75 | BTK (0.51) | BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914266-A | Novel 1H-pyrazolopyridine derivative and pharmaceutical composition comprising the same | 株式会社大熊制药 | 2020-03-24 | — | — | CN | disclosed |