Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | EP300 | Q09472 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CD40 | P25942 | 1/20 | 0.42 |
| ▸ | CD40LG | P29965 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 2/20 | 0.42 |
| ▸ | MAX | P61244 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22099924 | 1.00 | MAPT (0.51) | MAPTEP300HIF1ACD40CD40LG | |
| SCHEMBL20764701 | 0.92 | KMT2A (0.47) | MAPTEP300HIF1ACD40CD40LG | |
| SCHEMBL20764455 | 0.92 | KMT2A (0.47) | MAPTEP300HIF1ACD40CD40LG | |
| SCHEMBL20764703 | 0.92 | KMT2A (0.47) | MAPTEP300HIF1ACD40CD40LG | |
| SCHEMBL20764457 | 0.92 | KMT2A (0.47) | MAPTEP300HIF1ACD40CD40LG | |
| SCHEMBL20764499 | 0.89 | MAPT (0.47) | MAPTCD40CD40LGKMT2ANPC1 | |
| SCHEMBL20764501 | 0.89 | MAPT (0.47) | MAPTCD40CD40LGKMT2ANPC1 | |
| SCHEMBL20764530 | 0.87 | NR1H4 (0.38) | MAPTEP300KMT2ANPC1RAB9A | |
| SCHEMBL20764527 | 0.87 | NR1H4 (0.38) | MAPTEP300KMT2ANPC1RAB9A | |
| SCHEMBL22076684 | 0.87 | MAPT (0.48) | MAPTCD40CD40LGKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997627-A | Novel cystobacter amide derivatives | 亥姆霍兹感染研究中心有限公司 | 2020-04-10 | — | — | CN | disclosed |