Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213177 | 0.84 | NQO2 (0.59) | NQO2KMT2ALMNANPSR1MEN1 | |
| SCHEMBL317958 | 0.83 | NQO2 (0.58) | NQO2KMT2ALMNANPSR1MEN1 | |
| SCHEMBL28567770 | 0.81 | NQO2 (0.61) | NQO2KMT2ALMNANPSR1MEN1 | |
| SCHEMBL28092677 | 0.79 | NQO2 (0.53) | NQO2KMT2ALMNANPSR1MEN1 | |
| SCHEMBL8940303 | 0.76 | NQO2 (0.54) | NQO2KMT2ALMNANPSR1MEN1 | |
| SCHEMBL22721013 | 0.76 | KDM4E (0.49) | KMT2ALMNANPSR1MEN1L3MBTL1 | |
| SCHEMBL28384802 | 0.75 | NQO2 (0.53) | NQO2KMT2ALMNANPSR1MEN1 | |
| SCHEMBL182949 | 0.74 | NQO2 (0.66) | NQO2KMT2ALMNANPSR1MEN1 | |
| SCHEMBL30914171 | 0.74 | BCHE (0.52) | NQO2KMT2ALMNANPSR1MEN1 | |
| SCHEMBL30914170 | 0.74 | NQO2 (0.55) | NQO2KMT2ALMNANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117122600-A | Low dose brimonidine combination and uses thereof | 眼科治疗有限责任公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-114980839-A | Stable formulations of silk proteins | 蚕丝科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-113474011-A | Compositions and methods for promoting corneal tissue repair | 俄亥俄州立创新基金会 | 2021-10-01 | — | — | CN | disclosed |
| CN-110996954-A | Low dose brimonidine combinations and uses thereof | 眼科治疗有限责任公司 | 2020-04-10 | — | — | CN | disclosed |