Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.32 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 2/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560019 | 0.80 | GRIN3B (0.41) | LMNANR4A2SOS2 | |
| SCHEMBL22866830 | 0.80 | GRIN3B (0.41) | LMNANR4A2SOS2 | |
| SCHEMBL31745008 | 0.80 | NR4A2 (0.46) | LMNANR4A2SOS2CASP6 | |
| SCHEMBL29767078 | 0.80 | FLT1 (0.33) | PSMB8NR4A2SOS2CASP6 | |
| SCHEMBL2209771 | 0.80 | KIT (0.35) | PSMB8NR4A2SOS2KMT2ATDP1 | |
| SCHEMBL29544829 | 0.80 | MAP3K8 (0.36) | PSMB8LMNANR4A2SOS2CASP6 | |
| SCHEMBL13185442 | 0.80 | PSMB8 (0.32) | PSMB8NR4A2SOS2CASP6 | |
| SCHEMBL108770 | 0.80 | MAP3K8 (0.36) | PSMB8LMNANR4A2SOS2CASP6 | |
| SCHEMBL105732 | 0.80 | FLT1 (0.33) | PSMB8NR4A2SOS2CASP6 | |
| SCHEMBL29808576 | 0.80 | KIT (0.35) | PSMB8NR4A2SOS2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108659000-B | Heterocyclic compounds and process for preparing the same | 成都海创药业有限公司 | 2020-03-31 | — | — | CN | disclosed |