SCHEMBL28376644

SCHEMBL28376644

O=C(Nc1nc2ccccc2[nH]1)c1ccc(F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 14/20 1.00
RAB9A P51151 13/20 1.00
PKM P14618 7/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
TP53 P04637 2/20 1.00
KDM4E B2RXH2 1/20 1.00
HSD17B10 Q99714 1/20 1.00
MAOB P27338 1/20 0.78
ADORA2A P29274 1/20 0.78
KLF5 Q13887 3/20 0.75
SCD O00767 1/20 0.75
OPRK1 P41145 1/20 0.75
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
MTOR P42345 2/20 0.69
MAPT P10636 1/20 0.68
LMNA P02545 1/20 0.67
GAA P10253 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30334992 1.00 NPC1 (1.00) NPC1RAB9APKMSMN1; SMN2TP53
SCHEMBL11703736 0.93 NPC1 (0.91) NPC1RAB9APKMSMN1; SMN2TP53
SCHEMBL3926899 0.88 NPC1 (1.00) NPC1RAB9APKMSMN1; SMN2TP53
SCHEMBL11706930 0.87 NPC1 (0.86) NPC1RAB9APKMSMN1; SMN2TP53
SCHEMBL11705932 0.87 NPC1 (0.81) NPC1RAB9APKMSMN1; SMN2TP53
SCHEMBL11732060 0.86 NPC1 (0.76) NPC1RAB9APKMSMN1; SMN2TP53
SCHEMBL11705316 0.86 NPC1 (0.83) NPC1RAB9APKMSMN1; SMN2TP53
SCHEMBL11707899 0.86 SCD (1.00) NPC1RAB9APKMSMN1; SMN2TP53
SCHEMBL16562173 0.86 NPC1 (0.78) NPC1RAB9APKMSMN1; SMN2TP53
SCHEMBL11206434 0.86 NPC1 (1.00) NPC1RAB9APKMSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115915635-A Circuit board high-compactness protective film surface treatment method and circuit board 盐城市贝加尔电子材料有限公司 2023-04-04 CN claimed
CN-110965064-B Application of alkylamide benzimidazole compound, organic weldable protective agent, preparation method, use method and application thereof 深圳市贝加电子材料有限公司 2022-04-29 CN claimed
CN-110965064-A Application of alkylamide benzimidazole compound, organic weldable protective agent, preparation method, use method and application thereof 深圳市贝加电子材料有限公司 2020-04-07 CN claimed
CN-115915635-A Circuit board high-compactness protective film surface treatment method and circuit board 盐城市贝加尔电子材料有限公司 2023-04-04 CN disclosed
CN-110965064-B Application of alkylamide benzimidazole compound, organic weldable protective agent, preparation method, use method and application thereof 深圳市贝加电子材料有限公司 2022-04-29 CN disclosed
CN-110965064-A Application of alkylamide benzimidazole compound, organic weldable protective agent, preparation method, use method and application thereof 深圳市贝加电子材料有限公司 2020-04-07 CN disclosed