Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577518 | 0.87 | C5AR1 (0.47) | C5AR1 | |
| SCHEMBL30705775 | 0.85 | C5AR1 (0.61) | C5AR1 | |
| SCHEMBL28474770 | 0.80 | C5AR1 (0.65) | C5AR1 | |
| SCHEMBL21175427 | 0.75 | F12 (0.37) | C5AR1 | |
| SCHEMBL28376584 | 0.74 | C5AR1 (0.46) | C5AR1 | |
| SCHEMBL21446959 | 0.73 | C5AR1 (0.60) | C5AR1 | |
| SCHEMBL21175127 | 0.72 | F12 (0.35) | C5AR1 | |
| SCHEMBL21175373 | 0.72 | DPP4 (0.39) | C5AR1 | |
| SCHEMBL29079950 | 0.72 | C5AR1 (0.47) | C5AR1 | |
| SCHEMBL21175442 | 0.72 | DPP4 (0.45) | C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954525-B | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-111954525-A | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-110997674-A | 6-5 fused rings as C5a inhibitors | 凯莫森特里克斯股份有限公司 | 2020-04-10 | — | — | CN | disclosed |