Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP14 | P50281 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97113 | 0.78 | EPHX2 (0.47) | EPHX2MAPTACACB | |
| SCHEMBL28379652 | 0.75 | SCN10A (0.36) | SCN10A | |
| SCHEMBL28382354 | 0.75 | SCN10A (0.32) | SCN8ASCN10A | |
| SCHEMBL20638694 | 0.70 | EPHX2 (0.46) | SLC6A4SLC6A2SLC6A3SCN8ASCN10A | |
| SCHEMBL7588692 | 0.67 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3EPHX2MAPT | |
| SCHEMBL9654773 | 0.65 | PARP15 (0.42) | MAPT | |
| SCHEMBL28780452 | 0.65 | EPHX2 (0.50) | SLC6A4SLC6A2SLC6A3EPHX2MAPT | |
| SCHEMBL9422169 | 0.65 | PARP15 (0.42) | MAPT | |
| SCHEMBL17103390 | 0.65 | MAPT (0.32) | EPHX2MAPTACACB | |
| SCHEMBL17103328 | 0.65 | EPHX2 (0.32) | EPHX2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111065383-A | Carboxamides useful as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2020-04-24 | — | — | CN | disclosed |