Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726130 | 0.81 | TSHR (0.52) | SLC6A2TAAR1IDO1AGXTTSHR | |
| SCHEMBL10940340 | 0.81 | TSHR (0.52) | SLC6A2TAAR1IDO1AGXTTSHR | |
| SCHEMBL5016440 | 0.81 | TSHR (0.52) | SLC6A2TAAR1IDO1AGXTTSHR | |
| SCHEMBL11625744 | 0.81 | TSHR (0.52) | SLC6A2TAAR1IDO1AGXTTSHR | |
| SCHEMBL28384963 | 0.79 | SLC6A2 (0.45) | SLC6A2TAAR1IDO1AGXTTSHR | |
| SCHEMBL7023744 | 0.79 | TSHR (0.50) | SLC6A2TAAR1IDO1AGXTTSHR | |
| SCHEMBL17477217 | 0.78 | IDO1 (0.46) | SLC6A2TAAR1IDO1AGXTTSHR | |
| SCHEMBL11969533 | 0.78 | TAAR1 (0.44) | SLC6A2TAAR1IDO1AGXTTSHR | |
| SCHEMBL3579084 | 0.78 | TAAR1 (0.44) | SLC6A2TAAR1IDO1AGXTTSHR | |
| SCHEMBL23072564 | 0.77 | TSHR (0.48) | SLC6A2TAAR1IDO1AGXTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |