Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28387553 | 0.90 | BTK (0.56) | BTK | |
| SCHEMBL28380228 | 0.90 | BTK (0.59) | BTK | |
| SCHEMBL28379453 | 0.88 | BTK (0.57) | BTK | |
| SCHEMBL28379450 | 0.85 | BTK (0.57) | BTK | |
| SCHEMBL28379457 | 0.84 | BTK (0.57) | BTK | |
| SCHEMBL28384752 | 0.83 | BTK (0.64) | BTK | |
| SCHEMBL28887177 | 0.83 | BTK (0.58) | BTK | |
| SCHEMBL28384517 | 0.82 | BTK (0.56) | BTK | |
| SCHEMBL28384519 | 0.81 | BTK (0.56) | BTK | |
| SCHEMBL28384515 | 0.81 | BTK (0.56) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018865-B | 1-substituted benzyl pyrazolopyrimidine derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | claimed |
| CN-111018865-A | 1-substituted benzyl pyrazolopyrimidine derivative and preparation method and application thereof | 山东大学 | 2020-04-17 | — | — | CN | claimed |