Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19547910 | 0.85 | SLC22A12 (0.43) | SLC22A12FNTAFNTBAPPALDH1A1 | |
| SCHEMBL28389183 | 0.81 | SLC22A12 (0.66) | SLC22A12FNTAFNTBGAAKDM4E | |
| SCHEMBL17899882 | 0.80 | SLC22A12 (0.69) | SLC22A12 | |
| SCHEMBL28383942 | 0.79 | SLC22A12 (0.65) | SLC22A12FNTAFNTB | |
| SCHEMBL23111257 | 0.78 | SLC22A12 (0.62) | SLC22A12FNTAFNTB | |
| SCHEMBL28388337 | 0.78 | SLC22A12 (0.41) | SLC22A12FNTAFNTBGAAAPP | |
| SCHEMBL19435484 | 0.76 | SLC22A12 (0.53) | SLC22A12FNTAFNTBRAB9ASMN1; SMN2 | |
| SCHEMBL28887773 | 0.75 | FNTA (0.44) | SLC22A12FNTAFNTBRAB9ASMN1; SMN2 | |
| SCHEMBL28388332 | 0.75 | SLC22A12 (0.46) | SLC22A12HPGDNPSR1ALDH1A1 | |
| SCHEMBL28388350 | 0.74 | GAA (0.34) | SLC22A12FNTAFNTBGAAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108478-B | URAT1 inhibitors | 日本化学药品株式会社 | 2020-04-24 | — | — | CN | disclosed |