Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332530 | 0.84 | CDK5 (0.40) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL901326 | 0.84 | CDK5 (0.40) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL3825 | 0.84 | CDK5 (0.40) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| Water SCHEMBL1070875 | 0.82 | CDK5 (0.39) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL789094 | 0.82 | CDK5 (0.39) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL27882040 | 0.82 | CDK5 (0.39) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| Water SCHEMBL3935755 | 0.82 | CDK5 (0.39) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| Water SCHEMBL1888091 | 0.82 | CDK5 (0.39) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| Ammonia Solution, Strong SCHEMBL2074263 | 0.82 | CDK5 (0.39) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| Bicarbonate SCHEMBL5670827 | 0.80 | GRIN1 (0.41) | CDK5CDK5R1NR1I3GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697894-B2 | Preparation of taxanes from 9-dihydro-13-acetylbaccation III | ACCORD HEALTHCARE LTD. (CA) | 2014-04-15 | — | — | US | disclosed |
| US-8263793-B2 | Preparation of taxanes from 9-dihydro-13-acetylbaccatin III | ACCORD HEALTHCARE INC. (CA) | 2012-09-11 | — | — | US | disclosed |
| EP-1871753-B1 | PREPARATION OF TAXANES FROM 9-DIHYDRO-13-ACETYLBACCATIN III | ACCORD HEALTHCARE INC (CA) | 2012-07-18 | — | — | EP | disclosed |
| EP-2428510-A2 | Preparation of taxanes from 9-dihydro-13-acetylbaccatin III | Accord Healthcare Inc. (CA) | 2012-03-14 | — | — | EP | disclosed |
| US-20110144360-A1 | PREPARATION OF TAXANES FROM 9-DIHYDRO-13-ACETYLBACCATION III | ACCORD HEALTHCARE LTD. (CA) | 2011-06-16 | — | — | US | disclosed |
| EP-1871753-A4 | PREPARATION OF TAXANES FROM 9-DIHYDRO-13-ACETYLBACCATIN III | BIOXEL PHARMA INC (CA) | 2009-09-02 | — | — | EP | disclosed |
| US-20090062376-A1 | Preparation of Taxanes From 9-Dihydro-13-Acetylbaccatin III | BIOXEL PHARMA INC. (CA) | 2009-03-05 | — | — | US | disclosed |
| EP-1871753-A1 | PREPARATION OF TAXANES FROM 9-DIHYDRO-13-ACETYLBACCATIN III | Bioxel Pharma Inc. (CA) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006102758-A1 | PREPARATION OF TAXANES FROM 9-DIHYDRO-13-ACETYLBACCATIN III | BIOXEL PHARMA INC. (CA) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062376-A1 | Preparation of Taxanes From 9-Dihydro-13-Acetylbaccatin III | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, SIRT3, PARP9 | CDK5 1385/4885CDK5R1 1791/4885NR1I3 2272/4885 |
| US-20110144360-A1 | PREPARATION OF TAXANES FROM 9-DIHYDRO-13-ACETYLBACCATION III | SIRT3, NAT10, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CDK5 2475/4885CDK5R1 3204/4885NR1I3 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.