Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29627800 | 1.00 | LRRK2 (0.85) | LRRK2 | |
| SCHEMBL29627999 | 0.93 | LRRK2 (0.83) | LRRK2 | |
| SCHEMBL30231129 | 0.93 | LRRK2 (0.75) | LRRK2 | |
| SCHEMBL29627977 | 0.93 | LRRK2 (0.83) | LRRK2 | |
| SCHEMBL18606308 | 0.92 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL18658905 | 0.92 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL29627799 | 0.90 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL29627976 | 0.90 | LRRK2 (0.91) | LRRK2 | |
| SCHEMBL29627960 | 0.90 | LRRK2 (0.91) | LRRK2 | |
| SCHEMBL24027231 | 0.90 | LRRK2 (1.00) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051304-A | Novel imidazo [4,5-c ] quinoline derivatives as LRRK2 inhibitors | 辉瑞大药厂 | 2020-04-21 | — | — | CN | claimed |
| CN-111051304-A | Novel imidazo [4,5-c ] quinoline derivatives as LRRK2 inhibitors | 辉瑞大药厂 | 2020-04-21 | — | — | CN | disclosed |