Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228704 | 0.88 | NPC1 (0.72) | NPC1L3MBTL1APPCA12CA1 | |
| SCHEMBL31228779 | 0.88 | NPC1 (0.72) | NPC1L3MBTL1APPCA12CA1 | |
| SCHEMBL25307502 | 0.78 | APP (0.67) | CYP3A4APPSTAT3CA12CA1 | |
| SCHEMBL25306743 | 0.76 | MAOB (0.65) | CYP3A4APPMAOBKDM4EALDH1A1 | |
| SCHEMBL28573627 | 0.75 | APP (0.61) | CYP3A4APPSTAT3CA12CA1 | |
| SCHEMBL14877958 | 0.75 | APP (0.61) | CYP3A4APPSTAT3CA12CA1 | |
| SCHEMBL11460120 | 0.75 | CYP3A4 (0.86) | CYP3A4GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL12490321 | 0.75 | CYP3A4 (0.86) | CYP3A4GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL11460119 | 0.75 | CYP3A4 (0.86) | CYP3A4GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL11460121 | 0.75 | CYP3A4 (0.86) | CYP3A4GABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072597-B | Piperine derivative and preparation method and application thereof | 四川大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-111072597-A | Piperine derivative and preparation method and application thereof | 四川大学 | 2020-04-28 | — | — | CN | disclosed |