SCHEMBL28385367

SCHEMBL28385367

Cc1cc(O[Si](C)(C)C(C)(C)C)cc(C)c1-c1cccc(COc2ccc(C=O)s2)c1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28390893 0.86 FFAR1 (0.42) FFAR1
SCHEMBL28384643 0.83 FFAR1 (0.60) FFAR1
SCHEMBL12577899 0.82 FFAR1 (0.48) FFAR1
SCHEMBL15509492 0.77 FFAR1 (0.48) FFAR1
SCHEMBL28887876 0.76 FFAR1 (0.56) FFAR1
SCHEMBL28395207 0.75 FFAR1 (0.64) FFAR1
SCHEMBL3632679 0.74 NR1H2 (0.42) FFAR1
SCHEMBL2027100 0.74 BRD4 (0.49)
SCHEMBL28384722 0.72 FFAR1 (0.46) FFAR1
SCHEMBL5108435 0.71 FFAR1 (0.60) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107176944-B Thiophene carboxylic acid compound or derivative thereof, pharmaceutical composition, preparation method and application thereof 中国科学院上海药物研究所 2020-05-01 CN disclosed