⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370981 | 0.78 | — | — | |
| SCHEMBL22129330 | 0.73 | — | — | |
| SCHEMBL2162732 | 0.71 | — | — | |
| SCHEMBL8933027 | 0.71 | — | — | |
| SCHEMBL24492 | 0.69 | — | — | |
| SCHEMBL276996 | 0.69 | — | — | |
| SCHEMBL27637868 | 0.69 | — | — | |
| SCHEMBL14452292 | 0.69 | — | — | |
| SCHEMBL27791376 | 0.67 | — | — | |
| SCHEMBL275582 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667225-A | Compound (I) | 詹森药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115348883-A | Compounds and methods for treating duchenne muscular dystrophy | DTX医药有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-115297930-A | Antimicrobial compounds and methods | 库扎环球有限责任公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-112400014-B | Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators | 陶氏环球技术有限责任公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-114671864-A | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-114466848-A | Antibacterial compounds | 爱尔兰詹森科学公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-109311864-B | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114450288-A | 4-quinolinone antibacterial compounds | 爱尔兰詹森科学公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114423758-A | Antibacterial compounds | 爱尔兰詹森科学公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114340680-A | Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy | 坦博公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-107663206-B | Nitrogen-containing aromatic heterocyclic compound, preparation method thereof, pharmaceutical composition and application thereof | 上海璎黎药业有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-107922428-B | Thienopyrrole compounds and their use as inhibitors of oplophorus-derived luciferase | 普洛麦格公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-112218629-A | Bexarotene derivatives and their use in the treatment of cancer | DJ疗法有限责任公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-111818916-A | Macrocyclic MCL-1 inhibitors and methods of use | 艾伯维公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111788182-A | Muscarinic acetylcholine receptor M4Of (2) | 范德堡大学 | 2020-10-16 | — | — | CN | disclosed |
| CN-111565718-A | Antagonists of muscarinic acetylcholine receptor M4 | 范德比尔特大学 | 2020-08-21 | — | — | CN | disclosed |
| CN-111491920-A | Antagonists of muscarinic acetylcholine receptor M4 | 范德比尔特大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-106478634-B | Fused imidazole compounds, preparation method, pharmaceutical composition and use thereof | 尚华医药科技(江西)有限公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-111093708-A | Bioorthogonal compositions | 坦伯公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-110891569-A | Antagonists of muscarinic acetylcholine receptor M4 | 范德堡大学 | 2020-03-17 | — | — | CN | disclosed |