Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | ITK | Q08881 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28420729 | 0.92 | EGFR (0.43) | BTKEGFRITK | |
| SCHEMBL28387956 | 0.92 | EGFR (0.45) | EGFR | |
| SCHEMBL28383464 | 0.92 | BTK (0.47) | BTKEGFR | |
| SCHEMBL28383433 | 0.91 | EGFR (0.47) | BTKEGFRITK | |
| SCHEMBL28388722 | 0.90 | EGFR (0.45) | EGFR | |
| SCHEMBL28385547 | 0.89 | — | — | |
| SCHEMBL28887738 | 0.88 | EGFR (0.58) | EGFR | |
| SCHEMBL28385580 | 0.87 | FGFR1 (0.46) | BTKEGFRITK | |
| SCHEMBL28387194 | 0.86 | FGFR1 (0.45) | BTKEGFRITK | |
| SCHEMBL28384411 | 0.85 | BTK (0.45) | BTKEGFRITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | claimed |
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | disclosed |