Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 18/20 | 0.43 |
| ▸ | CDK2 | P24941 | 18/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 15/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389553 | 0.84 | CCNE1 (0.47) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL20883063 | 0.80 | CCNE1 (0.43) | CCNE1CDK2CDK5CDK5R1CNR2 | |
| SCHEMBL20877485 | 0.78 | CCNE1 (0.52) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL20877304 | 0.75 | CCNE1 (0.52) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29381312 | 0.74 | CCNE1 (0.48) | CCNE1CDK2CDK5CDK5R1CNR2 | |
| SCHEMBL20877375 | 0.73 | CCNE1 (0.47) | CCNE1CDK2CDK5CDK5R1CNR2 | |
| SCHEMBL22522942 | 0.71 | CCNE1 (0.47) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL20883053 | 0.71 | CCNE1 (0.60) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL24514061 | 0.69 | CCNE1 (0.42) | CCNE1CDK2CDK5CDK5R1CNR2 | |
| SCHEMBL20877486 | 0.69 | CCNE1 (0.45) | CCNE1CDK2CDK5CDK5R1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111148743-A | Inhibition of ubiquitin-specific peptidase 30 | 福马治疗有限公司 | 2020-05-12 | — | — | CN | disclosed |