Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 13/20 | 0.64 |
| ▸ | USP2 | O75604 | 3/20 | 0.57 |
| ▸ | USP8 | P40818 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17149218 | 0.79 | PHGDH (0.67) | PHGDHUSP2KMT2AMAPTALDH1A1 | |
| SCHEMBL15688701 | 0.78 | PHGDH (0.75) | PHGDHMAPTGAA | |
| SCHEMBL22616879 | 0.77 | USP2 (0.85) | PHGDHUSP2USP8KMT2AMAPT | |
| SCHEMBL29978391 | 0.76 | PHGDH (0.71) | PHGDHKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL29471320 | 0.76 | PHGDH (0.60) | PHGDHUSP2USP8KMT2AMAPT | |
| SCHEMBL663937 | 0.76 | PHGDH (0.71) | PHGDHKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL28400306 | 0.76 | PHGDH (0.60) | PHGDHUSP2USP8KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL28888697 | 0.76 | PHGDH (0.84) | PHGDHUSP2USP8KMT2AMAPT | |
| SCHEMBL29471335 | 0.76 | PHGDH (0.67) | PHGDH | |
| SCHEMBL15688956 | 0.76 | PHGDH (0.68) | PHGDHUSP2KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111166743-A | Anti-infection application of thiazole structure-containing compound | 中国医学科学院医药生物技术研究所 | 2020-05-19 | — | — | CN | claimed |
| CN-111166743-B | Anti-infection application of thiazole structure-containing compound | 中国医学科学院医药生物技术研究所 | 2022-03-22 | — | — | CN | disclosed |
| CN-111166743-A | Anti-infection application of thiazole structure-containing compound | 中国医学科学院医药生物技术研究所 | 2020-05-19 | — | — | CN | disclosed |