Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL2833687 | 0.96 | CA4 (0.47) | — | |
| Glycine SCHEMBL22442577 | 0.92 | — | — | |
| Glycine SCHEMBL3941224 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL6871848 | 0.92 | — | — | |
| Glycine SCHEMBL5943682 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL29062081 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL3863149 | 0.92 | — | — | |
| Glycine SCHEMBL2916896 | 0.92 | CA4 (0.50) | — | |
| Glycine SCHEMBL8096622 | 0.89 | CA4 (0.41) | — | |
| Glycine SCHEMBL5196769 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170463-B1 | SEEDS AND MARKERS FOR USE IN IMAGING | UNIV TEXAS (US) | 2015-03-18 | — | — | EP | disclosed |
| US-20140178297-A1 | Seeds and Markers for Use in Imaging | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-06-26 | — | — | US | disclosed |
| US-20130309167-A1 | Seeds and Markers for Use in Imaging | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2013-11-21 | — | — | US | disclosed |
| US-8529872-B2 | Seeds and markers for use in imaging | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-09-10 | — | — | US | disclosed |
| US-20100254897-A1 | Seeds and Markers for Use in Imaging | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-10-07 | — | — | US | disclosed |
| EP-2170463-A1 | SEEDS AND MARKERS FOR USE IN IMAGING | Board of Regents, The University Of Texas System (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009009760-A1 | SEEDS AND MARKERS FOR USE IN IMAGING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-01-15 | — | — | WO | disclosed |
| EP-1529775-B1 | Method for preparation of metal organic acid chelates | JH BIOTECH INC (US) | 2006-04-19 | — | — | EP | disclosed |
| EP-1529775-A1 | Method for preparation of metal organic acid chelates | JH Biotech, Inc. (US) | 2005-05-11 | — | — | EP | disclosed |
| US-6670494-B1 | Method for preparation of metal organic acid chelates | J H BROTECH, INC. | 2003-12-30 | — | — | US | disclosed |