Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20552269 | 0.83 | KMT2A (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20552353 | 0.82 | KMT2A (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20552315 | 0.79 | JAK2 (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20552627 | 0.79 | TSHR (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20552691 | 0.76 | ATM (0.51) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL20552090 | 0.76 | HPGD (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20552771 | 0.75 | MAPT (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20552426 | 0.74 | ATM (0.49) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL20552699 | 0.74 | MAPT (0.42) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL21764731 | 0.74 | SMN1; SMN2 (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132673-A | Non-fused tricyclic compounds | 维瓦斯治疗公司 | 2020-05-08 | — | — | CN | disclosed |