Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28841426 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL9408727 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL9408729 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL28132722 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL9069340 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL9069341 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL10875344 | 0.79 | CHRNA1 (0.65) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL9408584 | 0.78 | SMN1; SMN2 (0.73) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10483949 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10633808 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111165505-A | Use of eight-membered oxygen bridged heterocyclic compounds as bee selective insecticide synergists | 华东理工大学 | 2020-05-19 | — | — | CN | disclosed |