Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 3/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28403056 | 0.88 | FGFR3 (0.47) | FGFR3CHEK1FGFR1PDGFRBKDR | |
| SCHEMBL29050780 | 0.83 | FGFR3 (0.42) | FGFR3CHEK1FGFR1PDGFRBKDR | |
| SCHEMBL29050763 | 0.82 | FGFR3 (0.44) | FGFR3CHEK1FGFR1PDGFRBKDR | |
| SCHEMBL28400941 | 0.81 | FGFR3 (0.41) | FGFR3CHEK1FGFR1PDGFRBKDR | |
| SCHEMBL29050751 | 0.81 | FGFR3 (0.41) | FGFR3CHEK1FGFR1PDGFRBKDR | |
| SCHEMBL28399532 | 0.81 | PDGFRB (0.42) | FGFR3CHEK1FGFR1PDGFRBKDR | |
| SCHEMBL28399511 | 0.80 | PDGFRB (0.41) | FGFR3CHEK1FGFR1PDGFRBKDR | |
| SCHEMBL23326088 | 0.79 | FGFR3 (0.63) | FGFR3CHEK1FGFR1PDGFRBKDR | |
| SCHEMBL20625453 | 0.79 | FGFR3 (0.63) | FGFR3CHEK1FGFR1PDGFRBKDR | |
| SCHEMBL29050774 | 0.79 | FGFR3 (0.40) | FGFR3CHEK1FGFR1PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032643-B | Quinolinone compounds | 詹森药业有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-111032643-A | Quinolinone compounds | 詹森药业有限公司 | 2020-04-17 | — | — | CN | disclosed |