Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118654 | 0.85 | CYP1A2 (0.50) | USP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3945987 | 0.84 | USP2 (0.45) | USP2SMN1; SMN2HPGDEPHX2RECQL | |
| Hydrochloric Acid SCHEMBL2075849 | 0.84 | CYP1A2 (0.49) | USP2SMN1; SMN2 | |
| SCHEMBL1206712 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2HPGDEPHX2RECQL | |
| SCHEMBL484585 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2HPGDEPHX2 | |
| Hydrochloric Acid SCHEMBL896891 | 0.81 | USP2 (0.45) | USP2SMN1; SMN2HPGDEPHX2TSHR | |
| SCHEMBL3227260 | 0.81 | USP2 (0.42) | USP2SMN1; SMN2HPGDEPHX2RECQL | |
| SCHEMBL5316327 | 0.81 | USP2 (0.42) | USP2SMN1; SMN2HPGDEPHX2EPHX1 | |
| SCHEMBL8286 | 0.81 | USP2 (0.58) | USP2SMN1; SMN2HPGDEPHX2RECQL | |
| SCHEMBL1225127 | 0.81 | USP2 (0.58) | USP2SMN1; SMN2HPGDEPHX2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-110997678-A | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2020-04-10 | — | — | CN | disclosed |