SCHEMBL28399990

SCHEMBL28399990

CC(c1ccc(O)cc1)[C@@H](N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
NR1I2 O75469 1/20 0.44
PTGS1 P23219 1/20 0.44
ADRA1A P35348 1/20 0.44
LMNA P02545 1/20 0.44
BLM P54132 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SLC7A5 Q01650 2/20 0.44
SRC P12931 1/20 0.44
MME P08473 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
GRM8 O00222 1/20 0.41
GRM4 Q14833 1/20 0.41
APP P05067 1/20 0.41
CYP3A4 P08684 1/20 0.41
PRCP P42785 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31000618 1.00 ESR1 (0.46) ESR1ESR2PDCD1CD274NR1I2
SCHEMBL1868711 1.00 ESR1 (0.46) ESR1ESR2PDCD1CD274NR1I2
SCHEMBL31000596 1.00 ESR1 (0.46) ESR1ESR2PDCD1CD274NR1I2
SCHEMBL772054 1.00 ESR1 (0.46) ESR1ESR2PDCD1CD274NR1I2
Hydrochloric Acid SCHEMBL2523736 0.98 ESR1 (0.45) ESR1ESR2PDCD1CD274NR1I2
Hydrochloric Acid SCHEMBL15105482 0.98 ESR1 (0.45) ESR1ESR2PDCD1CD274NR1I2
SCHEMBL24156377 0.83 DPP4 (0.51) LMNASLC7A5SRCCYP2D6
SCHEMBL383452 0.83 DPP4 (0.51) LMNASLC7A5SRCCYP2D6
SCHEMBL180086 0.83 DPP4 (0.51) LMNASLC7A5SRCCYP2D6
SCHEMBL8882516 0.83 DPP4 (0.51) LMNASLC7A5SRCCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114269367-A Therapeutic peptides 科巴公司 2022-04-01 CN disclosed
CN-110997693-A Tau aggregation inhibitors 阿德克斯公司 2020-04-10 CN disclosed