Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.52 |
| ▸ | SLC33A1 | O00400 | 4/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012190 | 0.94 | PPARG (0.53) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1891361 | 0.92 | PPARG (0.52) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1886521 | 0.91 | PPARG (0.53) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1892638 | 0.91 | PPARG (0.57) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1891852 | 0.91 | PPARG (0.51) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1895839 | 0.90 | PPARG (0.57) | PPARGSLC33A1AGTR1 | |
| SCHEMBL4153671 | 0.90 | PPARG (0.51) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1890369 | 0.90 | SLC33A1 (0.50) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1899286 | 0.90 | PPARG (0.51) | PPARGSLC33A1 | |
| SCHEMBL13341664 | 0.90 | PPARG (0.53) | PPARGSLC33A1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256115-A1 | Heteromonocyclic compound and use thereof | Takeda Pharmaceutical Company Limited (JP) | 2010-12-01 | — | — | EP | disclosed |